Intracranial Pressure and Assessment Screening System (IPASS)

Intracranial Pressure and Assessment Screening System (IPASS)

Non-Invasive Intracranial Pressure (ICP) Monitoring

Military Need

The military needed a way for medics to measure intracranial pressure (ICP) non-invasively in the field. Vivonics' portable, non-invasive ICP monitor enables medics to measure ICP instantly in any battlefield condition.

Vivonics is developing IPASS: Intracranial Pressure Assessment and Screening System, a device that can monitor intracranial pressure completely non-invasively.  The system uses near-infrared sensors, the same type as used to record pulse oximetry.  Using a novel algorithm, the system provides a measure of intracranial pressure (ICP) within a few heartbeats. The IPASS portable ICP monitor can be used in clinical or field settings. 

IPASS enables the rapid assessment of intracranial pressure in post-concussion events.  A closed-head brain injury can have insidious effects on the casualty.  The brain is a soft organ with delicate structures held within a fixed volume.  Damage to the small structures within a brain causes local swelling, and cerebral blood flow and systemic blood pressure may not necessarily decrease with brain swelling.  Therefore, even mild swelling results in increased pressure.  This elevated intracranial pressure can itself cause more damage, leading to a negative spiral that ends in dire health consequences, including brain cell death and permanent brain injury or death.

Arguably the best systems currently available to identify which casualties are at the most risk of brain injury are those that monitor the physical trauma that the head experiences.  However these systems measure the severity of the cause (impact), which does not take into account individual variability with regards to susceptibility of brain injury. IPASS provides accurate, quick, and unobtrusive measurement of ICP.  In so doing, patients who require immediate attention can be attended to before further injury is incurred due to elevated pressure.  Rapid treatment, before worsening of symptoms, is likely to enable a faster return to activity, while minimizing the insidious long term effects of concussion-induced brain injury.

*Product under development, not yet FDA approved